Line optical tweezers instrument for measuring nanoscale interactions and kinetics
نویسندگان
چکیده
منابع مشابه
Line Optical Tweezers Instrument for Measuring Nanoscale Interactions and Kinetics
We describe an optical tweezers instrument for measuring short-ranged colloidal interactions, based on a combination of a continuous wave line optical tweezers, high speed video microscopy, and laser illumination. Our implementation can measure the separation of two nearly contacting microspheres to better than 4 nm at rates in excess of 10 kHz. A simple image analysis algorithm allows us to se...
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Efforts have been made to study the behavior of complex materials in micrometer dimensions with various techniques. One of these methods is the use of optical tweezers for biophysical applications. Red blood cells, as the most abundant blood-forming cells, play an important role in the life of living organisms, and their unique mechanical properties are important. In this report, the study of s...
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Optical tweezers instruments use the forces of laser radiation pressure to trap small particles. Using various techniques, these trapped particles can then be manipulated and forces on the objects in the trap can be measured. The forces that such an instrument is capable of measuring are of the order of one to 100 piconewtons (pN). While this technique has been used for over 20 years to manipul...
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Holographic optical tweezers have found many applications including the construction of complex micron-scale 3D structures and the control of tools and probes for position, force, and viscosity measurement. We have developed a compact, stable, holographic optical tweezers instrument which can be easily transported and is compatible with a wide range of microscopy techniques, making it a valuabl...
متن کاملMeasuring Trapping Forces in Optical Tweezers
Introduction Since the work of Ashkin on radiation pressure, the possibility to use the optical force of optical fields to trap and manipulate microparticles has found a wide range of applications. From atomic and nonlinear physics to biology, optical forces have provided a convenient way to control the dynamics of small particles.Optical tweezers, for example, have proved useful not only for t...
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ژورنال
عنوان ژورنال: Review of Scientific Instruments
سال: 2006
ISSN: 0034-6748,1089-7623
DOI: 10.1063/1.2387893